Laboratory testing of film-forming substances for the manufacture of ophthalmic medicinal films

In the manufacture of ophthalmic medicinal films, special attention should be paid to choice a film-forming substance, since both shape future film and its properties as whole depend on it. This article provides laboratory analysis with comparative assessment optimal concentrations two substances, polyvinyl alcohol gelatin. Most presented formers have number disadvantages, such thickness, insufficient strength elasticity, heterogeneity, formation cracks creases. One requirements for films is smoothness surface absence sharp corners. Based foregoing, we set goal study - conduct test substances films. An domestic foreign works gave reason use gelatin basis As result study, established (polyvinyl gelatin) that meet existing requirements. The concentration solution was ratio 1:7. addition plasticizer glycerol gelatinin mandatory. 1:15. Films from did not lose their shape, form or breaks when introduced into conjunctival sac. No irritant effect observed. Laying cause difficulties. Forms completely dissolved in eye 40 minutes, 90 minutes.